Phosbade® 800/400

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Phosbade® 800/400

Each Tablet contains Sevelamer Carbonate 800/400mg.

Phosbade®   is a phosphate binder used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption.

Mechanism Of Action

  • Phosbade® is a non-absorbed phosphate binding crosslinked polymer, free of metal and calcium.
  • Phosbade®contains multiple amines separated by one carbon from the polymer backbone. These amines exist in a protonated form in the intestine and interact with phosphate molecules through ionic and hydrogen bonding.
  • By binding phosphate in the gastrointestinal tract and decreasing absorption, sevelamer carbonate lowers the phosphate concentration in the serum (serum phosphorus).

As Directed by the Physician

  • Hyperphosphatemia
Adverse effects:
  • Nausea
  • Vomiting
  • Pain
  • Loss of appetite
  • Bloating
  • Diarrhea
  • Constipation,