Phosbade® 800/400
Each Tablet contains Sevelamer Carbonate 800/400mg.
Phosbade® is a phosphate binder used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption.
Mechanism Of Action
- Phosbade® is a non-absorbed phosphate binding crosslinked polymer, free of metal and calcium.
- Phosbade®contains multiple amines separated by one carbon from the polymer backbone. These amines exist in a protonated form in the intestine and interact with phosphate molecules through ionic and hydrogen bonding.
- By binding phosphate in the gastrointestinal tract and decreasing absorption, sevelamer carbonate lowers the phosphate concentration in the serum (serum phosphorus).
Dosage:
As Directed by the Physician
Indication:
- Hyperphosphatemia
Adverse effects:
- Nausea
- Vomiting
- Pain
- Loss of appetite
- Bloating
- Diarrhea
- Constipation,